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Scientists may have found the ‘holy grail’ of pain management: a non-addictive opioid

Last week, researchers dropped a bombshell report on DFNZ, a developing new medicine derived from a class of drugs once considered too dangerous to even study.

Their proposal sounded almost too good to be true: The drug might offer patients with chronic pain and injuries the benefits of an opioid without the threat of addiction or withdrawal.

In a thorough study of the effects of DFNZ on rats, the researchers observed that the drug had an obvious “reward” effect on the subjects, but at a certain point, the rodents easily stopped going back for more

The findings are especially timely, as Americans battle two crises that often overlap: chronic pain and opioid addiction. A 2018 scientific paper published in the Annual Review of Pharmacology and Toxicology found that more than 125 million Americans live with acute or chronic pain.

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