Young adults who received a Pfizer COVID-19 vaccine showed elevated spike protein production a year or more after vaccination — that’s significantly longer than the spike protein was expected to remain in the body — a peer-reviewed study showed.
The study, published last week in Immunity, Inflammation and Disease, found that participants exhibited elevated levels of multiple proinflammatory cytokines — proteins that help regulate the immune system — signifying “the persistence of the humoral immune response to messenger RNA (mRNA) vaccines.”
According to the study, “the persistent production of spike protein and highly inflammatory nature of mRNA-lipid nanoparticle” may account for the elevated cytokine levels.
Lipid nanoparticles are intended to deliver mRNA to human cells. But they’ve also been found to deliver DNA contaminants, contained within mRNA COVID-19 vaccines, throughout the body.
Study ‘raises important questions’ about long-term impact of COVID shots
“This study raises important questions about the long-term immunological imprinting of mRNA COVID-19 vaccines in healthy young adults,” TrialSite News reported.
TrialSite News founder and CEO Daniel O’Connor said the study’s findings “highlight the urgent need for spike protein clearance and biodistribution studies — especially in young males and older adults — whose immune responses appear disproportionately affected.”