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COVID-19 Vaccines ‘May Trigger’ Rheumatic Inflammatory Diseases: Study

A new review suggests that COVID vaccines “may trigger” rheumatic immune-mediated inflammatory diseases, including arthritis, vasculitis, lupus, and adult-onset Still’s disease.

On average, patients developed rheumatic diseases 11 days after vaccine administration, according to the study. Seventy-five (over 27 percent) of these patients experienced total disease remission, and about 50 percent improved following treatment. Eight were admitted to intensive care, and two died from their symptoms.

The short time span between COVID-19 vaccine administration and the onset of R-IMIDs suggests the potential possibility of a cause-and-effect relationship,” the authors wrote.

Rheumatic immune-mediated inflammatory diseases (R-IMIDs) involve inflammation that manifests in the joints, tendons, muscles, and bones due to an unknown cause.

The study, led by researchers from the National Health Service in the United Kingdom, examined 271 participants from 190 case studies published worldwide.

Over 80 percent of the patients developed symptoms after their first or second dose of the COVID-19 vaccine, and most were treated and improved with corticosteroids.

Almost 57 percent of the injured patients received the Pfizer vaccine, nearly a quarter received the AstraZeneca vaccine, and 12 percent of the rheumatic diseases manifested after the administration of the Moderna vaccine.

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