Janci Chunn Lindsay, Ph.D., is a molecular biologist and toxicologist and director of toxicology and molecular biology for Toxicology Support Services LLC. April 23, 2021, she delivered a three-minute public comment to the U.S. Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP).
Her expertise is analysis of pharmacological dose-responses, mechanistic biology and complex toxicity dynamics. In her ACIP comment (see video below), Lindsay described how she aided the development of a contraceptive vaccine in the 1990s that ended up causing unintended autoimmune destruction and sterility in animals which, despite careful pre-analysis, had not been predicted. She explains:
“We were developing what was meant to be a temporary contraceptive vaccine, which was very attractive because it prevented fertilization rather than preventing implantation — or it should have; that was the idea.